Satoshi Habuchi

Associate Professor, Bioscience

Biological and Environmental Science and Engineering Division

Education Profile

  • ​​​​​​Postdoctoral Fellow, Harvard Medical School, 2005
  • Postdoctoral Fellow, Katholieke Universiteit Leuven, 2001
  • Ph.D., Hokkaido University, 2001
  • M.Sc., Hokkaido University, 1999
  • B.Sc., Hokkaido University, 1997

Research Interests

​Dr. Habuchi’s research focuses on molecular imaging using advanced single-molecule fluorescence imaging and microscopy techniques in order to understand the hidden roles of static and dynamic disorders in complex systems. His research interests include cell adhesion, topological polymer dynamics, development of super-resolution fluorescence imaging methods, structural dynamics of proteins, photophysics and applications of light-emitting conjugated polymers, and fluorescent proteins.

Selected Publications

  • ​Serag, M. F,; Abadi, M.; Habuchi, S. "Single-molecule diffusion and conformational dynamics by spatial integration of temporal fluctuations", Nat. Commun., 2014, 5, 5123.
  • Loveland, A. B.; Habuchi, S; Walter, J. C.; van Oijen, A. M. "A general approach to break the concentration barrier in single-molecule imaging", Nat. Methods., 2012, 9, 987-992.
  • Habuchi, S.; Onda, S.; Vacha, M. "Molecular weight dependence of emission intensity and emitting sites distribution within single conjugated polymer molecules", Phys. Chem. Chem. Phys., 2011, 13, 1743-1753.
  • Habuchi, S.; Satoh, N.; Yamamoto, T.; Tezuka, Y.; Vacha, M. "Multimode diffusion of ring polymer molecules revealed by a single-molecule study", Angew. Chem. Int. Ed., 2010, 49, 1418-1421.
  • Habuchi, S.; Ando, R.; Dedecker, P.; Verheijen, W.; Mizuno, H.; Miyawaki, A.; Hofkens, "Reversible single-molecule photoswitching in the GFP-like fluorescent protein Dronpa", Proc. Natl. Acad. Sci. U.S.A. 2005, 102, 9511-9516.