Affiliations

• Bioscience

Education Profile

• ​​​​​​Postdoctoral Fellow, Harvard Medical School, 2005
  
• Postdoctoral Fellow, Katholieke Universiteit Leuven, 2001
• Ph.D., Hokkaido University, 2001
• M.Sc., Hokkaido University, 1999
• B.Sc., Hokkaido University, 1997
  

Research Interests

Dr. Habuchi’s research focuses on the development of tools and materials for fluorescence molecular imaging. His research interests include the development of microfluidics-based super-resolution fluorescence imaging platform for studying cellular interactions in the presence of external force, development of near-infrared/short wavelength fluorescent nanoparticles using conjugated polymers for single-molecule/particle imaging in tissues, and development of new single-molecule tracking methods to capture hidden nonrandom motion and conformational dynamics at the molecular level.

Selected Publications

• ​Piwonski, H.; Michinobu, T.; Habuchi, S. “Controlling photophysical properties of ultrasmall conjugated polymer nanoparticles through polymer chain packing”, Nat. Commun., 2017, 8, 15256.
  
• Serag, M. F.; Habuchi, S. “Conserved linear dynamics of single-molecule Brownian motion”, Nat. Commun., 2017, 8, 15675.
• Serag, M. F.; Abadi, M.; Habuchi, S. “Single-molecule diffusion and conformational dynamics by spatial integration of temporal fluctuations”, Nat. Commun., 2014, 5, 5123.
• Loveland, A. B.; Habuhi, S.; Walter, J. C.; van Oijen, A. M. “A general approach to break the concentration barrier in single-molecule imaging”, Nat. Methods, 2012, 9, 987-992.
• Habuchi, S.; Ando, R.; Dedecker, P.; Verheijen, W.; Mizuno, H.; Miyawaki, A.; Hofkens, J. “Reversible single-molecule photoswitcing in the GFP-like fluorescent protein Dronpa”, Proc. Natl. Acad. Sic. USA, 2005, 102, 9511-9516.