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Moussa Benhamed

Assistant Professor, Plant Science 
Biological and Environmental Science and Engineering Division
Center membership : 
Desert Agriculture


Affiliations

Education Profile

  • ​​​​Ph.D. in Cell Biology from Ecole Pratique des Hautes Etude (EPHE), Paris in 2009.​

Research Interests

Dr. Moussa Benhamed is experienced in working in both plant and human models systems, but has now dedicated his efforts to understanding the interface between signaling and epigenetics in plants with a focus on how this is mediated via stress response, a topic that has excellent synergy with the research plan of the Center for Desert Agriculture.

His research interests include plant development, stress, cell cycle, epigenetics, chromatin organization, histone modification and non coding RNA. The objective of his team is to better understand the role of chromatin remodeling and epigenetic regulation in plant stress response.

Selected Publications

  • Ariel F, Jegu T, Latrasse D, Romero-Barrios N, Christ A, Benhamed M, Crespi M. "Noncoding transcription by alternative RNA polymerases dynamically regulates an auxin-driven chromatin loop." Mol Cell. 2014 Aug 7;55(3):383-96. doi: 10.1016/j.molcel.2014.06.011. Epub 2014 Jul 10.
  • Jégu T, Latrasse D, Delarue M, Hirt H, Domenichini S, Ariel F, Crespi M, Bergounioux C, Raynaud C, Benhamed M. "The BAF60 subunit of the SWI/SNF chromatin-remodeling complex directly controls the formation of a gene loop at FLOWERING LOCUS C in Arabidopsis." Plant Cell. 2014 Feb;26(2):538-51. doi: 10.1105/tpc.113.114454. Epub 2014 Feb 7.
  • Jégu T, Latrasse D, Delarue M, Mazubert C, Bourge M, Hudik E, Blanchet S, Soler MN, Charon C, De Veylder L, Raynaud C, Bergounioux C, Benhamed M. "Multiple functions of Kip-related protein5 connect endoreduplication and cell elongation." Plant Physiol. 2013 Apr;161(4):1694-705. doi: 10.1104/pp.112.212357. Epub 2013 Feb 20.
  • Neyret-Kahn H, Benhamed M, Ye T, Le Gras S, Cossec JC, Lapaquette P, Bischof O, Ouspenskaia M, Dasso M, Seeler J, Davidson I, Dejean A. "Sumoylation at chromatin governs coordinated repression of a transcriptional program essential for cell growth and proliferation." Genome Res. 2013 Oct;23(10):1563-79. doi: 10.1101/gr.154872.113. Epub 2013 Jul 26.
  • Benhamed M, Herbig U, Ye T, Dejean A, Bischof O. "Senescence is an endogenous trigger for microRNA-directed transcriptional gene silencing in human cells." Nat Cell Biol. 2012 Feb 26;14(3):266-75. doi: 10.1038/ncb2443.