Postdoctoral Associate, Massachusetts Institute of Technology, USA, 2021
Postdoctoral Fellow, Massachusetts Institute of Technology, USA, 2020
Ph.D. Bioengineering, Imperial College London, UK, 2019
B.Eng. and M.Eng. Biomedical Engineering, Imperial College London, UK, 2015
Dr Al-Sulaiman's research focuses on the development of next generation biosensing platforms to detect an emerging class of disease biomarkers called cell-free nucleic acids including microRNA and cell-free DNA. At the intersection between polymeric biomaterials and microtechnologies, her research includes advancements in hydrogel beads, microparticles, microneedles and microarrays. She is also interested in single-molecule detection technologies, namely nanopore sensors, for the detection and characterization of rare disease biomarkers.
Dr Al-Sulaiman's research aims to tackle urgent clinical needs including early detection and monitoring of cancer and Alzheimer's disease in addition to understanding the skin microbiome.
Al Sulaiman, Dana, Alfie Gatehouse, Aleksandar P. Ivanov, Joshua B. Edel, and Sylvain Ladame. "Length-Dependent, Single-Molecule Analysis of Short Double-Stranded DNA Fragments through Hydrogel-Filled Nanopores: A Potential Tool for Size Profiling Cell-Free DNA." ACS Applied Materials & Interfaces (2021).
Al Sulaiman, Dana, Sarah J. Shapiro, Jose Gomez-Marquez, and Patrick S. Doyle. "High-Resolution Patterning of Hydrogel Sensing Motifs within Fibrous Substrates for Sensitive and Multiplexed Detection of Biomarkers." ACS Sensors (2020).
Al Sulaiman, Dana, Jason YH Chang, Nitasha R. Bennett, Helena Topouzi, Claire A. Higgins, Darrell J. Irvine, and Sylvain Ladame. "Hydrogel-coated microneedle arrays for minimally invasive sampling and sensing of specific circulating nucleic acids from skin interstitial fluid." ACS Nano 13, no. 8 (2019): 9620-9628.
Al Sulaiman, Dana, Paolo Cadinu, Aleksandar P. Ivanov, Joshua B. Edel, and Sylvain Ladame. "Chemically modified hydrogel-filled nanopores: a tunable platform for single-molecule sensing." Nano Letters 18, no. 9 (2018): 6084-6093.
Al Sulaiman, Dana, Jason YH Chang, and Sylvain Ladame. "Subnanomolar detection of oligonucleotides through templated fluorogenic reaction in hydrogels: controlling diffusion to improve sensitivity." Angewandte Chemie International Edition 56, no. 19 (2017): 5247-5251.