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Brande Wulff

Associate Professor, Plant Science

Biological and Environmental Science and Engineering Division 
Center membership :
Center for Desert Agriculture

brande.wulff@kaust.edu.sa
The Wulff Lab


Affiliations

Education Profile

  • Postdoc, IBMP-CNRS, Strasbourg, France, 2008
  • Human Frontiers Postdoc Fellow, IBMCP-CSIC, Spain, 2005
  • EMBO Postdoc Fellow, IBMCP-CSIC, Spain, 2004
  • PhD, The Sainsbury Laboratory, UK, 2001
  • BSc, University of East Anglia, UK, 1997

Research Interests

​Brande's research programme explores the genetics of disease resistance in wheat. This has led to developing fast, new and efficient methods for gene discovery and cloning which use mutant and natural populations followed by sequence alignment to locate genes. Brande has also co-developed a method for halving the generation time of wheat and other crops, in a controlled environment, dramatically speeding up capabilities for research and breeding purposes. His long-term aim is to use cloned genes from wild ancestors of wheat to engineer durable resistance to these diseases in cultivated wheat.

Selected Publications

  • The wheat stem rust resistance gene Sr43 encodes an unusual protein kinase. Yu G, Matny O, Gourdoupis S, Rayapuram N, Aljedaani FR, Wang YL, Nürnberger T, Johnson R, Crean EE, Saur IM-L, Gardener C, Yue Y, Kangara N, Steuernagel B, Hayta S, Smedley M, Harwood W, Patpour, M, Wu S, Poland J, Jones JDG, Reuber TL, Ronen M, Sharon A, Rouse MN, Xu S, Holušová K, Bartoš J, Molnár I, Karafiátová M, Hirt H, Blilou I, Jaremko Ł, Doležel J, Steffenson BJ, Wulff BBH Nature Genetics 2023, 1-6.

  • Reference genome-assisted identification of stem rust resistance gene Sr62 encoding a tandem kinase, Yu G, Matny O, Champouret N, Steuernagel B, Moscou MJ, Hernández-Pinzón I, Green P, Hayta S, Smedley M, Harwood W, Kangara N, Yue Y, Gardener C, Manfield MJ, Olivera PD, Welchin C, Simmons J, Millet E, Minz-Dub A, Ronen M, Avni R, Sharon A, Patpour M, Justesen Af, Jayakodi M, Himmelbach A, Stein N, Wu S, Poland J, Ens J, Pozniak C, Karafiátová M, Molnár I, Doležel J, Ward ER, Reuber TL, Jones JDG, Mascher M, Steffenson BJ, Wulff BBH, Nature Communications, 2022, 13:1607.

  • Population genomic analysis of Aegilops tauschii identifies targets for bread wheat improvement, Gaurav K, Arora S, Silva P, Sánchez-Martín J, Horsnell R, Gao L, Brar GS, Widrig V, Raupp J, Singh N, Wu S, Kale Sm, Chinoy C, Nicholson P, Quiroz-Chávez J, Simmonds J, Hayta S, Smedley MA, Harwood W, Pearce S, Gilbert D, Kangara N, Gardener C, Forner-Martínez M, Liu J, Yu G, Boden S, Pascucci A, Ghosh S, Hafeez An, O'hara T, Waites J, Cheema J, Steuernagel B, Patpour M, Justesen AF, Liu S, Rudd JC, Avni R, Sharon A, Steiner B, Pkirana RP, Buerstmayr H, Mehrabi AA, Nasyrova FY, Chayut N, Matny O, Steffenson BJ, Sandhu N, Chhuneja P, Lagudah E, Elkot AF, Tyrrell S, Bian X, Davey RP, Simonsen M, Schauser L, Tiwari VK, Kutcher HR, Hucl P, Li A, Liu D-C, Mao L, Xu S, Brown-Guedira G, Faris J, Dvorak J, Luo M-C, Krasileva K, Lux T, Artmeier S, Mayer KFX, Uauy C, Mascher M, Bentley AR, Keller B, Poland J, Wulff BBH, Nature Biotechnology, 2022, 40:422–431.

  • Creation and judicious application of a wheat resistance gene atlas, Hafeez AN, Arora S, Ghosh S, Gilbert D, Bowden RL, Wulff BBH, Molecular Plant, 2021, 14:1053–1070.

  • Resistance gene cloning from a wild crop relative by sequence capture and association genetics, Arora S, Steuernagel B, Gaurav K, Chandramohan S, Long Y, Matny O, Johnson R, Enk J, Periyannan S, Narinder S, Hatta MAMD, Athiyannan N, Cheema J, Yu G, Kangara N, Ghosh S, Szabo LJ, Poland J, Bariana H, Jones JDG, Bentley AR, Ayliffe M, Olson E, Xu SS, Steffenson BJ, Lagudah E, Wulff BBH, Nature Biotechnology, 2019, 37:139-143.