Gordon Bell Prize for Climate Modelling, Association for Computing Machinery (ACM), 2024

Gauss Award for High Performance Computing, German Supercomputer Centers, 2020

Gordon Bell Prize, Association of Computing Machinery, 1999

Fellow, American Mathematical Society, 2012

Fellow, Society for Industrial and Applied Mathematics, 2011

SIAM Prize for Distinguished Service to the Profession, 2011

Distinguished Faculty Teaching Award, Columbia University, 2008

Sidney Fernbach Award, IEEE Computer Society, 2007

Prize for Teaching Excellence in the Natural Sciences, Yale University, 1991

Junior Faculty Fellowship, Yale University, 1990

NSF Presidential Young Investigator Award, 1989

Danforth Award for Excellence in Teaching, Harvard University, 1982

Hayes-Palmer Prize in Engineering, Princeton University, 1978

Career Achievement Award, Euro-Par Conference, 2018

R. Yokota, G. Turkiyyah & D. Keyes, "Communication Complexity of the Fast Multipole Method and its Algebraic Variants", Supercomput. Front. and Innov., 1:62–83, 2014.

D. Keyes et al. "Multiphysics Simulations: Challenges and Opportunities", Int. J. High Performance Computing Applications 27:5–83, 2013.

D. E. Keyes. "Exaflop/s – the Why and the How", Comptes Rendus 339:70–77, 2011.

D. A. Knoll & D. E. Keyes. "Jacobian-Free Newton-Krylov Methods: A Survey of Approaches and Applications", J. Comput. Phys., 193:357–397, 2004.

X.-C. Cai & D. E. Keyes. "Nonlinear Preconditioned Inexact Newton Algorithms", SIAM J. Sci. Comp. 24:183–200, 2002.