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KAUST Catalysis Center, KCC
Division of Chemical and Life Sciences & Engineering
4700 King Abdullah University of Science and Technology
Thuwal 23955-6900
Kingdom of Saudi Arabia

Jörg Eppinger

Assistant Professor, Chemical Science

Catalysis Research Center

Ph.D. Chemistry, Technische Universität München, Germany, 1999

B.S. Chemistry, Technische Universität München, Germany, 1996

Research Interests

In the Green Chemistry & Catalysis Laboratories (GCC-Labs), Professor Eppinger and his team are developing homogeneous and bio-catalytic methods to establish sustainable protocols for selective catalytic processes. As a general concept, the GCC-Labs investigate and combine molecular processes of living cells with the tools and principles of chemistry to design and create novel, highly selective and effective catalysts. Currently active research projects span the interface of organometallic chemistry, microbiology and materials science.

These research projects include;

  • development of green chemistry protocols,
  • rapid generation of highly selective, catalytically active organometallic enzyme hybrids (OMEHs) based on artificial co-factors or incorporation of unnatural amino acids,
  • application of electro-active motives or microbes targeting e.g. carbon dioxide conversion or generation of efficient fuel cell cathode surfaces
  • synthesis of peptide-metal conjugates for intelligent catalyst support, nanostructured hybrid materials and enzyme microarrays for activity determination using on fluorescent or electrochemical detection

Selected Publications

  • Marziale, AN, Jantke D, Faul SH, Reiner T, Herdtweck E, Eppinger J, "An efficient protocol for the palladium catalyzed Suzuki-Miyaura cross-coupling reaction". Green Chemistry, 13: 169–177, 2011.
  • Gräwert T, et al. "Probing the reaction mechanism of IspH protein by x-ray structure analysis". Proceedings of the National Academy of Science, 107: 1077–1081, 2010.
  • Eppinger J, et al. "Alkyl complexes of rare-earth metal centers supported by chelating 1,1'Diamidoferrocene ligands: synthesis, structure and applications in methacrylate polymerization". Organometallics, 73: 2290–2296, 2008.
  • Funeriu DP, Eppinger J, Denizot L, Miyake M, Miyake J, "Enzyme family-specific and activity-based screening of chemical libraries using enzyme microarrays". Nature Biotechnology, 23: 622–627, 2005.
  • Eppinger J, Funeriu DP, Miyake M, Denizot L, Miyake J, "Enzyme microarrays: on-chip determination of inhibition constants based on affinity-label detection of enzymatic activity". Angewandte Chemie International Edition, 43: 3806–3810, 2004.